![]() ![]() According to the bacterial resistance, it can be divided into single drug resistance and multidrug resistance. Bacteria can be resistant to a certain class of antibiotics, or to a variety of antibiotics with different chemical structures. The characteristics of bacterial resistance is a major problem in the treatment of infectious diseases. Pathogens in nature, such as a strain of bacteria, may also have natural resistance. Drug resistance can be divided into acquired drug resistance and natural drug resistance according to its causes. Once drug resistance occurs, the chemotherapeutic effect of the drug is significantly reduced. Plasmid-mediated deletion of IMP-1 metallo- β-lactamase binding outer membrane protein is one of the main reasons for the decrease of antibiotic sensitivity. The results showed that the enzyme-linked immunosorbent assay titer of acrB antibody was 1:40,000, and the preparation of acrB antibody was successful. coli J53 to carbapenems was slightly higher than that of kpn6617. In the sensitivity comparison, Escherichia coli J53 was more sensitive to these two antibiotics, minimum inhibitory concentration values were 0.5 and 0.25 μg/ml, respectively. The sequence types of kpn6099 and kpn6617 were the same. Multisite sequence typing showed that 5 carbapenem-resistant Klebsiella pneumoniae belonged to 4 different types. 87.5% of the samples were resistant to piperacillin. All strains were resistant to ceftazidime, ceftriaxone, ertapenem, and aztreonam. Finally, the data were statistically analyzed. Drug resistance phenotype test, drug sensitivity test, and conjugation test were used to observe the drug sensitivity results and the titer of acrB antibody. ![]() ![]() Carbapenem Enterobacteriaceae bacteria isolated from a hospital from January 2015 to June 2020 were selected. To investigate the mechanism of antibiotic resistance in Enterobacteriaceae. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |